NCAA Football Initial Betting Line Announced For Michigan vs. MSU Published October 24, 2021 With a top 7 matchup between Michigan and Michigan state set for this weekend, the Wolverines open as a 4-point favorite heading to East Lansing: Michigan opens as a 4-point favorite over Michigan State, via @CircaSports. — Scott Bell (@sbell021) October 24, 2021 In this article: Recent Posts Looks Like Michigan Is Going To Miss Out On Key Offensive Playmaker Once Favoring Wolverines Surprising Team Has Reported Best Odds To Land No. 1 Recruit Jackson Cantwell MSU Apparently Committed NCAA Violations In The Funniest Way Michigan Could Add A Major WR Who Just Entered Transfer Portal New Leader With Top RB Recruit Javian Osborne Who Is Deciding Between Michigan, Notre Dame?